| Autor: |
Michael, Robin L., Klorman, Rafael, Salzman, Leonard F., Borgstedt, Agneta D., Dainer, Karen B. |
| Předmět: |
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| Zdroj: |
Psychophysiology; Nov1981, Vol. 18 Issue 6, p665-677, 13p |
| Abstrakt: |
Evoked potentials during the X and B-X versions of the Continuous Performance Test (CPT) were evaluated in 29 hyperactive children after ingestion of placebo or methylphenidate (0.3 mg/Kg). Twenty-one age matched normal children were also assessed twice but without any drugs. In both tests, placebo-treated hyperactives made more omission and commission errors and displayed smaller late positive components (LPC) of the evoked response to salient experimental cues. Methylphenidate ameliorated hyperactives' performance in both tasks and enlarged their LPCs in CPT-X. Several of these drug effects and diagnostic differences were absent for older hyperactive subjects, probably because some of the procedures were too easy for them. For younger patients the present tasks were sufficiently challenging, and the results reflect normalization of their deficits in sustained attention. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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