| Autor: |
Han Yue Zheng, Alsager, Omar A., Wood, Cameron S., Hodgkiss, Justin M., Plank, Natalie O. V. |
| Předmět: |
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| Zdroj: |
Journal of Vacuum Science & Technology: Part B-Nanotechnology & Microelectronics; Nov/Dec2015, Vol. 33 Issue 6, p06F904-1-06F904-8, 8p |
| Abstrakt: |
The authors demonstrate a small molecule 17 β-estradiol (E2) sensor based on aptamer functionalized carbon nanotube network film field effect transistors (CNT FETs). The real time current response for the 35-mer E2 aptamer functionalized CNT FET shows a clear increase in current over the range of 50nM to 1.6 μM of E2. The E2 response using a longer 75-mer version of the aptamer functionalized CNT FETs, where the aptamer/E2 binding occurs beyond the Debye length, shows no obvious evidence of sensing. The CNT FET sensing platform has been fabricated via a simple surfactant free solution processing route, compatible with further carbon nanotube functionalization to develop a versatile sensing platform. The CNT FET aptasensors are able to perform real time monitoring of E2 levels for selective and quantitative detection of E2 in liquids. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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