Synthesis and antibacterial properties of 4-bromobenzohydrazide derivatives and crystal structure of ( E)- N′-((1 H-indol-3-yl)methylene)-4-bromobenzohydrazide.

Autor:	Chantrapromma, S., Ruanwas, P., Noonot, T., Horkaew, J., Boonnak, N., Ghabbour, H., Fun, H.-K.
Předmět:	ANTIBACTERIAL agents AZIDE derivatives AZIDE synthesis CRYSTAL structure CONDENSATION reactions X-ray diffraction HYDROGEN bonding
Zdroj:	Crystallography Reports; Dec2015, Vol. 60 Issue 7, p1072-1079, 8p
Abstrakt:	Six 4-bromobenzohydrazide derivatives ( 1-6) were synthesized by the condensation reaction of 4-bromobenzohydrazide and benzaldehydes, and evaluated for antibacterial activity. Their structures were determined by spectroscopic methods. In addition, the crystal structure of compound 6 was characterized by single crystal X-ray structure determination. In crystal packing, the molecules are linked by N-H···O and N-H···N hydrogen bonds into two-dimensional network parallel to the (001) plane. The crystal is further stabilized by weak C-H···O and C-H···π interactions. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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