| Autor: |
Stekkinger, E, Scholten, RR, Heidema, WM, Spaanderman, MEA |
| Předmět: |
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| Zdroj: |
BJOG: An International Journal of Obstetrics & Gynaecology; Dec2015, Vol. 122 Issue 13, p1773-1780, 8p |
| Abstrakt: |
Objective: To determine the prevalence of recurrent pre-eclampsia in women with a history of pre-eclampsia with both metabolic syndrome and low plasma volume postpartum, as compared with women without either entity.Design: Retrospective cohort study.Setting: Three tertiary referral hospitals in the Netherlands.Population: Women with a history of pre-eclampsia.Methods: In 196 women with a history of pre-eclampsia we determined the presence or absence of metabolic syndrome using the World Health Organization criteria and measured plasma volume with the (125) I-human serum albumin indicator dilution technique. We compared the prevalence of recurrent pre-eclampsia in four groups, classified according to presence or absence of metabolic syndrome and low or normal plasma volume, calculating odds ratios (OR), adjusted for confounders.Main Outcome Measure: Recurrence of pre-eclampsia in the subsequent pregnancy.Results: The prevalence of recurrent pre-eclampsia was 12% (12/99) in women without metabolic syndrome with normal plasma volume, versus 47% (8/17) in women with both metabolic syndrome and low plasma volume: OR 6.44 (95% CI 2.09-19.90), adjusted OR 7.90 (95% CI 2.30-27.16). Recurrent pre-eclampsia was present in 44% (10/23) and 25% (14/57) of women with isolated metabolic syndrome and low plasma volume, respectively.Conclusions: In the concomitant presence of metabolic syndrome and low plasma volume, the prevalence of recurrent pre-eclampsia was nearly 50%, which is four times as high as the prevalence in women without either entity.Tweetable Abstract: Metabolic syndrome and low plasma volume raise the risk of recurrent pre-eclampsia to nearly 50%. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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