| Autor: |
Müller-Späth, Thomas, Angarita, Monica, Baur, Daniel, Lievrouw, Roel, Lissens, Geert, Ströhlein, Guido, Bavand, Michael, Morbidelli, Massimo |
| Předmět: |
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| Zdroj: |
International Labmate; Jan2014, Vol. 39 Issue 1, p4-6, 3p |
| Abstrakt: |
A novel twin column counter-current chrormatography process was used for the capture of monoclonal antibodies (mAbs) from clarified cell culture harvest. The process features improved performance in terms of productivity, buffer consumption, product concentration and capacity utilisation compared to traditional batch chromatography. As presented in this case study, the advantages become more pronounced as loading flow velocities are increased. Due to its cyclic nature, the CaptureSMB process is very well suited for the integration with conventional batch-wise as well as with continuous processing. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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