Abstrakt: |
Background: Hypothermia is an important determinant of the survival of newborns, especially among low-birth-weight babies. Prolonged hypothermia leads to edema, general hemorrhage, jaundice and death. So this study has afforded to examine effective factors on passing the hypothermia state. Materials and Methods: Our sample consists of 439 neonates that were hospitalized in NICU, at Emam Khomeini hospitals of Tehran. The neonate's rectal temperature was measured immediately after birth and every 30 minutes after that, until neonate passed hypothermia stage. In order to estimate the rate of transition from state of neonatal hypothermia, we used multi-state Markov model with two covariates, newborn baby birth weight and environmental temperature. We used R package to fit the model. Results: Estimated transition rates from severe hypothermia and mild hypothermia were 0.1192 per minute and 0.0549 per minute, respectively. Weight had a significant effect on transition from hypothermia stage to normal stage (%95 confidence interval (0.1364, 0.4165), (p-value<0.001). Environmental temperature affected the transition from hypothermia stage to normal stage; significantly %95 confidence interval for parameter of Environmental temperature is (0.0439, 0.4963), (p-value<0.001). Conclusions: Results showed that, the neonates with normal weight and neonate in an environmental temperature higher than 28o C had a bigger transition rate from hypothermia stage. [ABSTRACT FROM AUTHOR] |