Immunologic conditions and infectious complications in colon and rectal surgery for neoplasms.

Autor: Fragapane, P., Varvello, G., Bossotti, M., Vergara, V., Poccardi, G.
Zdroj: Diseases of the Colon & Rectum; Apr1990, Vol. 33 Issue 4, p302-304, 3p
Abstrakt: The authors evaluated the peroperative immunologie state of patients with colorectal tumors and controlled the postoperative incidence of infections. Twenty-one patients were studied, and delayed type hypersensitivity reactivity determined by the CMI multitest (Merieux) eight days before and eight days after surgery. A lymphocytogram was performed using monoclonal antibodies. A significant percentage of patients were anergic preoperatively. Immunologic analysis revealed lymphocytosis in the first postoperative period. The largest absolute quantitative increase was shown by NK CD16+ cells. It is possible that the results, obtained by dynamic monitoring of the main parameters of cellular immunity, will offer a new way for prognostic evaluation of surgical risk. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index