Skeletal muscle basal AMP-activated protein kinase activity is chronically elevated in alloxan-diabetic dogs: impact of exercise.

Autor: Christopher, Michael J., Zhi-Ping Chen, Rantzau, Christian, Kemp, Bruce E., Alford, Frank P.
Předmět:
Zdroj: Journal of Applied Physiology; Oct2003, Vol. 95 Issue 4, p1523-1530, 8p, 1 Chart, 3 Graphs
Abstrakt: Examines the effect of diabetes and exercise on skeletal muscle AMP-activated protein kinase (AMPK)U.S. Occupational Safety and Health Administration α1 AND -α2 activities and site-specific phosphorylation of acetyl-CoA carboxylase in the same six dogs before alloxan-induced diabetes and after four to five weeks of suboptimally controlled hyperglycemic and hypoinsulinemic diabetes in the presence and absence of 300-minute phlorizin-induced normoglycemia.
Databáze: Complementary Index