Structure Formation in Fibrous Materials Based on Poly-3-Hydroxybutyrate for Traumatology.

Autor: Olkhov, A. A., Sklyanchuk, E. D., Staroverova, O. V., Abbasov, T. A., Guryev, V. V., Akatov, V. S., Fadeyeva, I. S., Fesenko, N. I., Filatov, Yu. N., Iordanskii, A. L.
Předmět:
Zdroj: AIP Conference Proceedings; 2015, Vol. 1683 Issue 1, p020167-1-020167-4, 4p, 1 Black and White Photograph, 2 Graphs
Abstrakt: The paper reviews the structure formation of fibrous materials based on poly-3-hydroxybutyrate depending on parameters of electrospinning and characteristics of polymer solution. Fiber structure was studied by DSC, ESR and SEM. The molecular weight affects the diameter and uniformity of the fiber. An electromechanical impact leads to an orientation of crystalline structure in the fiber. The design of an artificial bioresorbable implant based on nano- and microfibers of poly-3-hydroxybutrate is created. Dynamics of growth of mesenchymal stem cells on poly-3-hydroxybutrate scaffolds is studied. Successful field tests of implants of the Achilles tendon in Wistar rats are conducted. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index