| Autor: |
KANNAN, NANDINI, RANGASWAMY, MANJUNATHA, KEMAPAIAH, BETTADAIAH |
| Předmět: |
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| Zdroj: |
Journal of Chemical Sciences; Aug2015, Vol. 127 Issue 8, p1405-1410, 6p |
| Abstrakt: |
Microwave-assisted dehydration-oxidation of β-bromo- tert-alcohols to afford 2,3-unsaturated ketones in good yield is reported. The reaction of substrates with DMSO in 1:1 ratio (w/v) is promoted by ZnS in a solvent-free condition. A concurrent bi-functional activation of trans-vicinal bromo- and hydroxyl groups with ZnS is elucidated. This is a new observation under microwave and applies to β-bromo- tert-alcohols derived from 1,4-disubstitued-1-cyclohexenes. It is very useful in the synthesis of 2,3-unsaturated ketones derived from monoterpenes which are valuable flavour compounds. [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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