| Autor: |
Inoue, Seijiro, Ikeda, Osamu, Nakasone, Yutaka, Beppu, Toru, Masuda, Toshiro, Yokoyama, Koichi, Utsunomiya, Daisuke, Baba, Hideo, Yamashita, Yasuyuki |
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| Zdroj: |
Acta Radiologica; Nov2015, Vol. 56 Issue 11, p1361-1367, 7p |
| Abstrakt: |
Background: Percutaneous transhepatic portal embolization (PTPE) can induce atrophy of the embolized- and hypertrophy of the residual area. These effects are advantageous in patients scheduled for extended hepatectomy.Purpose: To evaluate the clinical safety and effectiveness of foam sclerotherapy with foam ethanolamine oleate (EO) and carbon dioxide (CO2) for PTPE before hepatectomy.Material and Methods: We performed sclerotherapy for PTPE in 15 patients with: hepatocellular carcinoma (HHC; n = 9), bile duct carcinoma (n = 5), or metastatic liver tumor from colon cancer (n = 1). The foam contained 5% EO iopamidol (EOI) and CO2 at a 1:2 ratio. We compared the percentage of the pre- and post-PTPE future liver remnant (FLR) volumes and calculated the percent FLR volume (%FLR) increase after PTPE.Results: The amount of EOI used (range, 14-20 mL; median, 16.8 mL) was based on the volume of the target portal vein. Technical success was achieved in 14 of 15 patients (93%); the other patient presented with computed tomography evidence of recanalization 1 week after PTPE. The FLR volume before and after portal vein embolization was 599 ± 342 and 691 ± 318 cm(3), respectively (P < 0.01); the mean %FLR volume increase was 29.5%. There was no significant difference in the mean platelet count, total bilirubin, total aspartate aminotransferase, and total creatinine before and after PTPE. One patient suffered intra-abdominal bleeding that required transcatheter arterial embolization. No other patients developed major complications higher than grade 3.Conclusion: Sclerotherapy using foam EOI and CO2 is clinically safe and effective for PTPE before hepatectomy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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