Genomic characterization and regulation of CYP3al3: role of xenobiotics and nuclear receptors.

Autor: Sayeepriyadarshini Anakk, Kalsotra, Auinash, Qi Shen, Vu, Mary T., Staudinger, Jeffrey L., Davies, Peter J.A., Strobel, Henry W.
Předmět:
Zdroj: FASEB Journal; Sep2003, Vol. 17 Issue 12, p1736, 3p, 2 Diagrams, 3 Graphs
Abstrakt: Focuses on a study which characterized the genomic structure of mouse cytochromes P450 (CYP) 3a13 in order to identify the molecular basis of CYP3a regulation. Way in which CYP have been demonstrated; Responsibility of the CYP3A subfamily; Analysis of the catalytic ability of expressed CYP3a13 toward clinically active drugs.
Databáze: Complementary Index