Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors.

Autor: Pai, Rama, Nakamura, Toshikazu, Moon, Woo S., Tarnawski, Andrzej S.
Předmět:
Zdroj: FASEB Journal; Sep2003, Vol. 17 Issue 12, p1640, 8p, 4 Color Photographs, 3 Black and White Photographs, 5 Graphs
Abstrakt: Provides evidence that PGE[sub2] transactivates Cox-2, hepatocyte growth factor receptor, increases tyrosine phosphorylation and nuclear accumulation of B-catenin. Factors that drive colon cancer invasion; Function of prostaglandins; Event that occurs in cancer progression.
Databáze: Complementary Index