Alterations of the Birt-Hogg-Dube gene (BHD) in sporadic colorectal tumuors.

Autor: Kahnoski, K., Khoo, S. K, Nassif, N. T., Chen, J., Lobo, G. P., Segelov, E., Teh, B. T.
Předmět:
Zdroj: Journal of Medical Genetics; Jul2003, Vol. 40 Issue 7, p511-515, 5p, 1 Diagram, 1 Chart, 1 Graph
Abstrakt: Focuses on the alterations of the Birt-Hogg-Dube (BHD) gene in sporadic colorectal tumors. Microsatellite instability of one polypeptide and seven carcinomas; Identification of two novel missense mutations in two microsatellite stable carcinomas; Involvement of the BHD gene in tumorigenesis of a subset of microsatellite sporadic colorectal carcinomas.
Databáze: Complementary Index