Effects of Transcutaneous Electrical Acupoint Stimulation on Patients with Stable Chronic Obstructive Pulmonary Disease: A Prospective, Single-Blind, Randomized, Placebo-Controlled Study.

Autor:	Liu, Xuemei, Fan, Tao, Lan, Ying, Dong, Shoujing, Fu, Juanjuan, Mao, Bing
Předmět:	DIAGNOSIS of dyspnea OBSTRUCTIVE lung disease treatment WALKING ACTIVE oxygen in the body ACUPUNCTURE points ALTERNATIVE medicine LONGITUDINAL method PROBABILITY theory RESEARCH funding RESPIRATORY measurements PULMONARY function tests STATISTICAL sampling STATISTICAL hypothesis testing T-test (Statistics) TRANSCUTANEOUS electrical nerve stimulation STATISTICAL power analysis STATISTICAL significance BODY mass index RANDOMIZED controlled trials VISUAL analog scale TREATMENT effectiveness PRE-tests & post-tests VITAL capacity (Respiration) BLIND experiment DATA analysis software DESCRIPTIVE statistics
Zdroj:	Journal of Alternative & Complementary Medicine; Oct2015, Vol. 21 Issue 10, p610-616, 7p, 1 Diagram, 2 Charts, 1 Graph
Abstrakt:	Objectives: To evaluate the clinical effect of transcutaneous electrical nerve stimulation over acupoints (acu-TENS) on patients with stable chronic obstructive pulmonary disease (COPD). Design: Prospective, single-blind, randomized, placebo-controlled study. Settings/Locations: Outpatient center of West China Hospital, Sichuan University. Patients: Fifty patients with stable COPD enrolled in the study. Interventions: Patients were randomly assigned to one of two groups: the acu-TENS group ( n=25), who underwent acu-TENS over acupoints of bilateral EX-B-1( Dingchuan), BL-13 ( Feishu), BL-23 ( Shenshu), ST-36 ( Zusanli), and the placebo acu-TENS control group ( n=25), who had the same electrode placement but no electrical output. Treatments were performed for 40-minute sessions every 2 days for 4 weeks. Outcome measures: Lung function (forced expiratory volume in 1 second, percentage predicted (FEV1% predicted); forced vital capacity, percentage predicted (FVC% predicted), 6-minute walk distance (6MWD) and oxygen saturation (SpO2), COPD assessment test (CAT), and Dyspnea Visual Analogue Scale (DVAS) were assessed before and after the intervention. Results: Compared to control group, FEV1% predicted was improved and CAT score was decreased significantly in the acu-TENS group after treatment ( p<0.05). The DVAS score decreased significantly in the acu-TENS group ( p=0.039), with a slight but insignificant improve in 6MWD, SpO2, and FVC% predicted after treatment. Conclusions: Acu-TENS over acupoints of bilateral EX-B-1 ( Dingchuan), BL-13 ( Feishu), BL-23 ( Shenshu), and ST-36 ( Zusanli) improved FEV1% predicted and reduced DVAS and CAT scores on patients with stable COPD. This may be a novel treatment strategy in COPD. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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