Structural self-organization of C60 and cisplatin in physiological solution.

Autor: Prylutskyy, Yu. I., Cherepanov, V. V., Evstigneev, M. P., Kyzyma, O. A., Petrenko, V. I., Styopkin, V. I., Bulavin, L. A., Davidenko, N. A., Wyrzykowski, D., Woziwodzka, A., Piosik, J., Kaźmierkiewicz, R., Ritter, U.
Zdroj: Physical Chemistry Chemical Physics (PCCP); 10/21/2015, Vol. 17, p26084-26092, 9p
Abstrakt: The specific features of structural self-organization of C60 fullerene and antitumor drug cisplatin (Cis) in physiological solution (0.9% NaCl) have been investigated by means of small-angle neutron scattering, scanning electron and atomic force microscopies, as well as isothermal titration calorimetry, dynamic light scattering and UV-Vis spectroscopy. The formation of C60 + Cis complexes, has been reported, unveiling the mechanism of medico-biological synergy observed during administration of the mixture of these drugs. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index