Treatment failure by canakinumab in a patient with progressive multisystemic Erdheim-Chester disease refractory to anakinra: successful use of vemurafenib.

Autor:	Schirmer, Jan H., Thorns, Christoph, Moosig, Frank, Holle, Julia U.
Předmět:	PROTEIN kinase inhibitors BIOPSY MAGNETIC resonance imaging POSITRON emission tomography DISEASE remission NON-langerhans-cell histiocytosis THERAPEUTICS
Zdroj:	Rheumatology; Oct2015, Vol. 54 Issue 10, p1932-1934, 3p, 1 Diagram
Abstrakt:	A letter to the editor is presented in response to a case report by T-A Tran et al which describes the efficacy of canakinumab, a mAb directed against human IL-1B in Erdheim-Chester disease (ECD).
Databáze:	Complementary Index
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