Health-related quality of life in children with objectively diagnosed staple food allergy assessed with a disease-specific questionnaire.

Autor: Protudjer, JLP, Jansson, S‐A, Östblom, E, Arnlind, M Heibert, Bengtsson, U, Dahlén, S‐E, Kallström‐Bengtsson, I, Marklund, B, Middelveld, RJM, Rentzos, G, Sundqvist, AC, Åkerström, J, Ahlstedt, S
Zdroj: Acta Paediatrica; Oct2015, Vol. 104 Issue 10, p1047-1054, 8p
Abstrakt: Aim: Among Swedish children of 0-12 years old, we investigated various food allergy-related exposures associated with health-related quality of life using a food allergy-specific questionnaire among children allergic to the staple foods cow's milk, hen's egg and/or wheat, and contextualised worse food allergy-associated health-related quality of life using a generic questionnaire versus controls.Methods: In total, 85 children with objectively diagnosed allergy to the staple foods were included as cases, and 94 children matched for age and sex were included as controls. We administered a food allergy-specific parent-completed questionnaire originally developed by EuroPrevall to cases only, and a generic health-related quality of life questionnaire (EuroQol Health Questionnaire, 5 Dimensions; EQ 5-D); to both cases and controls.Results: Hen's egg was the most common offending staple food, affecting 76% of cases. Approximately 7% of cases were allergic to all three staple foods. Parent-reported respiratory and cardiovascular symptoms were associated with worse health-related quality of life. Elements of disease severity [previous anaphylaxis (p < 0.001); epinephrine autoinjector prescription (p < 0.003)] were negatively associated with health-related quality of life. Cases had worse health-related quality of life measured by the EQ-5D compared to controls (p < 0.01).Conclusion: The use of a disease-specific questionnaire revealed that disease severity in children with objectively diagnosed allergy to the staple foods cow's milk, hen's egg and/or wheat is associated with worse health-related quality of life. The use of a generic questionnaire confirmed that cases have worse health-related quality of life than controls. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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