| Autor: |
Lecerf-Schmidt, Florine, Haudecoeur, Romain, Peres, Basile, Ferreira Queiroz, Marcos Marçal, Marcourt, Laurence, Challal, Soura, Ferreira Queiroz, Emerson, Sotoing Taiwe, Germain, Lomberget, Thierry, Le Borgne, Marc, Wolfender, Jean-Luc, De Waard, Michel, Robins, Richard J., Boumendjel, Ahcène |
| Předmět: |
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| Zdroj: |
Chemical Communications; 10/4/2015, Vol. 51 Issue 77, p14451-14453, 3p |
| Abstrakt: |
Tramadol has recently been isolated from the roots and bark of Nauclea latifolia. A plausible biosynthetic pathway has been proposed and the product–precursor relationship has been probed by 13C position-specific isotope analysis. By further exploring this pathway, we demonstrate that a key step of the proposed pathway can be achieved using mild conditions that mimic in vivo catalysis. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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