| Autor: |
Toombs-Ruane, L.J., Riley, C.B., Rosanowski, S.M., Kendall, A.T., Hill, K.E., Benschop, J. |
| Zdroj: |
Equine Veterinary Journal; Sep2015 Supplement, Vol. 47, p3-3, 0p |
| Abstrakt: |
Reasons for performing study Guidelines for the rational use of antimicrobials enable practitioners to improve antimicrobial stewardship and slow the development of antimicrobial resistance ( AMR) [1]; these must be regionally relevant [2]. New Zealand ( NZ) is geographically isolated and the importance of AMR on equine studs is unknown. Objectives To identify AMR patterns of bacteria isolated from NZ foals so as to provide regionally specific information for the development of antimicrobial stewardship guidelines. Study design Retrospective study of clinical pathology records. Methods A database search of bacterial culture submissions from foals <3 weeks of age from April 2004 to December 2013 was completed. Culture results, antimicrobial sensitivities, and demographic factors were tabulated. The Kirby-Bauer disk diffusion susceptibility test was used to define sensitivity. Multi-drug resistance ( MDR) was defined as non-sensitivity to 3 or more core antimicrobials in a panel (ceftiofur, enrofloxaxin, gentamicin, penicillin [not included for Gram-negative bacteria], tetracycline, trimethoprim- sulfamethoxazole). Results Bacterial isolates (n = 127) were cultured from 64/102 (62.7%) of foal submissions. Four bacterial groups ( Staphylococcus spp., Streptococcus spp., Enterococcus spp. and Escherichia coli) accounted for 100 (79%) of bacterial isolates cultured. At least one or 2 MDR isolates were cultured from 24 (38%) and 8 (12%) foals, respectively. Culture positive and negative foals were demographically similar. Conclusions A significant number of bacterial isolates from foals have reduced antimicrobial susceptibility to commonly used antimicrobial drugs. The results are of concern from treatment and stewardship perspectives. Multi-drug resistance was found, indicating a need for regionally relevant antimicrobial use recommendations. Ethical animal research: Not applicable. Sources of funding: Massey University McGeorge fund; New Zealand Equine Research Foundation. Competing interests: None declared. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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