| Autor: |
Šála, Michal, Dejmek, Milan, Procházková, Eliška, Hřebabecký, Hubert, Rybáček, Jiří, Dračínský, Martin, Novák, Pavel, Rosenbergová, Šárka, Rosenberg, Ivan, Nencka, Radim |
| Předmět: |
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| Zdroj: |
Synthesis; 2015, Vol. 47 Issue 17, p2609-2616, 8p |
| Abstrakt: |
Taurine (2-aminoethanesulfonic acid) is a representative substructure in biologically active compounds, but can raise difficulties in direct coupling reactions. In this study, the synthesis of taurine-derived sulfonic acids and analogous aromatic sulfonic acids was accomplished by a performic acid promoted oxidation of corresponding symmetrical disulfide precursors. In some of the products, the taurine or sulfanilic acid nitrogen atom is incorporated in a heterocyclic scaffold or part of a peptide bond in dipeptide mimetics. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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