| Autor: |
Kolundžić, Filip, Murali, Annamalai, Pérez‐Galán, Patricia, Bauer, Jonathan O., Strohmann, Carsten, Kumar, Kamal, Waldmann, Herbert |
| Předmět: |
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| Zdroj: |
Angewandte Chemie International Edition; 7/28/2014, Vol. 53 Issue 31, p8122-8126, 5p |
| Abstrakt: |
A facile synthesis of chiral cyclic alkyl aminocarbene- gold(I) complexes from gold-free 1,7-enyne substrates was developed. The novel cyclization-rearrangement reaction sequence is triggered by the addition of (Me2S)AuCl to different 1,7-enynes and leads to structurally unique carbene- gold(I) complexes in high yields. These novel complexes are catalytically active and inhibit the proliferation of different human cancer cell lines. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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