| Autor: |
Yin, Wei, Cheng, Lingping, Chai, Huihui, Guo, Ruiqiang, Liu, Renhua, Chu, Changhu, Palasota, John, Cai, Xiaohui |
| Předmět: |
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| Zdroj: |
Analytical & Bioanalytical Chemistry; Aug2015, Vol. 407 Issue 20, p6217-6220, 4p |
| Abstrakt: |
A silica-based stationary phase bearing both hydrophilic hydroxyl and amino groups was developed by covalently bonding a small molecular N, N-dimethylamino 1,3-propanediol moiety onto silica beads via copper(I)-catalyzed Huisgen azide-alkyne 1,3-dipolar cycloaddition (CuAAC). This new stationary phase showed good HILIC characteristics and high column efficiency (the theoretical plate number is up to 37000 plates m in the case of inosine) in the separation of polar compounds, such as nucleosides and bases, organic acids, cephalosporins, and carbapenems. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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