Targeted expression of shibire[supts] and semaphorin 1a reveals critical periods for synapse formation in the giant fiber of Drosophila.

Autor: Murphey, R. K., Froggett, Stephen J., Caruccio, Phyllis, Shan-Crofts, Xiaoliang, Kitamoto, Toshihiro, Godenschwege, Tanja A.
Předmět:
Zdroj: Development (09501991); Aug2003, Vol. 130 Issue 16, p3671, 12p, 8 Color Photographs, 3 Charts
Abstrakt: Presents a study which determined the timing of events during the assembly of a neural circuit in Drosophila by targeting expression of the temperature-sensitive shibire gene to the giant fiber (GF) system and disruption of endocytosis. Materials and methods used; Development of the GF system; Production of axonal phenotypes from endocytosis; Dynamics of GF retraction and regeneration; Interactions between shibire and semaphorin.
Databáze: Complementary Index