Automated production and quality testing of [F]labeled radiotracers using the BG75 system.

Autor: Anzellotti, Atilio, Bailey, Jim, Ferguson, Doug, McFarland, Aaron, Bochev, Pavel, Andreev, Georgiy, Awasthi, Vibhudutta, Brown-Proctor, Clive
Předmět:
Zdroj: Journal of Radioanalytical & Nuclear Chemistry; Aug2015, Vol. 305 Issue 2, p387-401, 15p, 5 Color Photographs, 1 Black and White Photograph, 1 Diagram, 1 Chart, 2 Graphs
Abstrakt: The simplification and automation of clinical PET radiotracer production, from isotope production to quality control, can streamline the current manufacturing workflow and, at the same time minimize the investment needed. In this article we present pre-clinical and clinical results showing the feasibility for manufacture of [F]fluoride labeled radiotracers such as [F]FDG, [F]NaF and [F]FMISO under automated conditions using the BG75 system. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index