Synthesis of Halogenated 9-(Dihydroxycyclopent-4′-enyl) Adenines and Their Inhibitory Activities Against S-Adenosylhomocysteine Hydrolase.

Autor:	Shin Jeong, Lak, Gyu Park, Jae, Choi, Won Jun, Moon, Hyung Ryong, Lee, Kang Man, Kim, Hea Ok, Kim, Hee-Doo, Chun, Moon Woo, Park, Hea-Young, Kim, Kilhyoun, Sheen, Yhun Y.
Předmět:	ADENINE HYDROLASES HOMOCYSTEINE RIBOSE METHYL groups
Zdroj:	Nucleosides, Nucleotides & Nucleic Acids; May2003, Vol. 22 Issue 5-8, p919-921, 3p
Abstrakt:	Novel halovinyl analogues of neplanocin A without 4′-hydroxymethyl group were easily synthesized starting from d-ribose via cyclopentenone 5 as a key intermediate and their inhibitory activity against SAH hydrolase was assayed. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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