Tailoring a two-dimensional graphene oxide surface: dual T1 and T2 MRI contrast agent materials.

Autor: Peng, Erwin, Wang, Fenghe, Tan, Suhui, Zheng, Bingwen, Li, Sam Fong Yau, Xue, Jun Min
Zdroj: Journal of Materials Chemistry B; 7/28/2015, Vol. 3 Issue 28, p5678-5682, 5p
Abstrakt: A generalized strategy for developing a hybrid two-dimensional nanostructured dual T1–T2 MRI contrast agent (CA), by co-loading graphene oxide with both Mn-doped Fe3O4 (T2 agent) and MnO (T1 agent) magnetic nanoparticles, is reported. Typical T1/T2 signal quenching, due to magnetic coupling, was not observed because of the fair T1 CA separation distance from the T2 CA on the graphene oxide. The resultant two-dimensional nanostructured MRI CA complements the existing dual T1–T2 MRI CA libraries. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index