Glycemic Control in Pharmacist-Managed Insulin Titration Versus Standard Care in an Indigent Population.
| Autor: | Pitlick, Jamie M., Brooks, Amie D. |
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| Předmět: |
MEDICAL care
BLOOD pressure BLOOD sugar CHI-squared test CHOLESTEROL CONFIDENCE intervals DIABETES FISHER exact test GLYCOSYLATED hemoglobin HIGH density lipoproteins INSULIN LOW density lipoproteins MEDICALLY uninsured persons METABOLIC regulation HEALTH outcome assessment PATIENTS PHARMACISTS PROBABILITY theory SOCIAL role STATISTICAL hypothesis testing T-test (Statistics) TRIGLYCERIDES SAMPLE size (Statistics) RETROSPECTIVE studies CASE-control method DATA analysis software |
| Zdroj: | Diabetes Spectrum; Fall2011, Vol. 24 Issue 4, p211-217, 7p |
| Abstrakt: | Purpose. To assess the impact of a pharmacist-managed insulin titration program on achieving clinical goals in an underserved population with diabetes. Methods. The study included 35 subjects followed in a pharmacist-managed insulin titration and 35 matched control subjects. Control subjects were followed under standard procedures within the same clinic and were matched for age, titration time frame, and insulin regimen. The primary outcome was change in A1C between the two groups at 6 months. Secondary outcomes included change in A1C within groups at 3, 6, 9, and 12 months, as well as the proportion of subjects attaining a goal A1C of < 7% and adhering to preventive care recommendations. Results. Between-group comparison demonstrated a significant absolute difference in mean change in A1C at 6 months favoring pharmacist management (0.9%, 95% CI 0.2-1.6, P = 0.009). Within-group comparisons demonstrated significant A1C reduction from baseline at 6 months (-1.1%, 95% CI -1.7 to -0.4, P = 0.002), 9 months (-1.4%, 95% CI -2.0 to -0.7, P < 0.001), and 12 months (-1.3%, 95% CI -2.0 to -0.5, P = 0.001) in the pharmacist- managed group with no significant changes observed in the control group. Conclusion. Pharmacist-managed insulin titration resulted in significant improvement in glycemic control compared to standard care in an indigent population. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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