| Autor: |
Leonardi NM, Casale GA, Nicolini J, Zubata PD, Salgueiro MJ, Zubillaga MB, Leonardi, Natalia M, Casale, Guillermo A, Nicolini, Jorge, Zubata, Patricia D, Salgueiro, María J, Zubillaga, Marcela B |
| Zdroj: |
Journal of Nuclear Medicine Technology; Dec2012, Vol. 40 Issue 4, p271-274, 4p |
| Abstrakt: |
Unlabelled: The aim of the present work was to validate a paper chromatography system as an alternative way to determine the radiochemical purity of Na(18)F.Methods: The evaluated parameters were specificity, limit of quantification, measurement interval, linearity, precision, accuracy, and robustness.Results: The proposed method proved to be linear (P > 0.05; r(2) = 1.000), precise (relative SD, 8.6%), accurate (mean recovery, 95.9%; relative SD, 1.5%-1.8%), and robust under different conditions since no influence of the operative variables on the chromatographic performance was observed.Conclusion: This system can be used as a reliable alternative method to determine the radiochemical purity of Na(18)F samples that can be easily performed in PET radiopharmacies at low cost. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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