| Autor: |
McCracken, Ardythe A., Brodsky, Jeffrey L. |
| Předmět: |
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| Zdroj: |
BioEssays; Sep2003, Vol. 25 Issue 9, p868-877, 10p, 2 Diagrams, 1 Chart |
| Abstrakt: |
Studies the evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD), a component of the protein quality control system. Complex sequence of events in which unwanted proteins are selected in the ER and exported to the cytosol for degradation by the proteasome; Molecular mechanisms of ERAD; Role of ERAD in the metabolic regulation and biomedical implications. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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