| Autor: |
Charton, Isabelle, Suzenet, Franck, Boutin, Jean A., Audinot, Valérie, Delagrange, Philippe, Bennejean, Caroline, Renard, Pierre, Guillaumet, Gérald |
| Předmět: |
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| Zdroj: |
Journal of Enzyme Inhibition & Medicinal Chemistry; Apr2003, Vol. 18 Issue 2, p187-193, 7p |
| Abstrakt: |
The synthesis of benzoxathiins bearing a retroamide function is described from 8-hydroxythiochroman, the key step involving the synthesis of the benzoxathiin ring through a sulfonium salt. These new melatonin analogues were evaluated on human receptors MT 1 and MT 2 and have a similar affinity to that of melatonin itself. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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