| Autor: |
Avlia, A., Serrado, A., Reig, L., Famades, A., Maho, P. |
| Předmět: |
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| Zdroj: |
European Journal of Neurology; Sep2003, Vol. 10 Issue 5, p601, 1p |
| Abstrakt: |
Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT) is usually underdiagnosed. The term applied to most cases has been 'Hashimoto's encephalopathy.' Its presentation varies from focal neurological deficits to global confusion, often in association with myoclonus. To gain insight into the early events occurring in SREAT, researchers describe a case of a patient with an early gait disturbance and upper myoclonus as her predominant presentation symptoms. A diagnosis of subclinical hypothyroidism was made based on the patient's blood chemistry: thyroid-stimulating hormones 9.8 mIU/l and free thyroxine 11.82 pmol/l. The patient was treated orally with 25 μg/day of levothyroxine. Whilst over the following 6 months there was no evidence for further cognitive function deterioration her walking abilities continued to be impaired. The introduction of steroids resulted in a dramatic but temporary improvement. The patient died 6 weeks later. |
| Databáze: |
Complementary Index |
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