| Abstrakt: |
The incidence of multiple congenitalmalformations amid infants of mothers withinsulindependent diabetes mellitus (type I or IDDM) isbetween 6% and 12%. This is two to five timesthe incidence in nondiabetic mothers.Congenital malformations associated with IDDMinclude craniofacial defects, holoprosencephaly,cardiac defects, caudal regression syndrome,renal agenesis, gastrointestinal defects, and asingle umbilical artery. Unfortunately, thesemalformations are not exclusive to IDDMpregnancies. Many of the same pathologies are alsoseen in trisomy 13 fetuses. [ABSTRACT FROM AUTHOR] |
