| Autor: |
Rello J, Lorente C, Diaz E, Bodi M, Boque C, Sandiumenge A, Santamaria JM, Rello, Jordi, Lorente, Carmen, Diaz, Emili, Bodi, Maria, Boque, Carmen, Sandiumenge, Albert, Santamaria, Josep Maria |
| Zdroj: |
CHEST; Dec2003, Vol. 124 Issue 6, p2239-2243, 5p |
| Abstrakt: |
Objective: To determine the epidemiology of pneumonia in patients with tracheotomy receiving short-term mechanical ventilation.Design: Observational prospective study.Setting: A 14-bed medical-surgical ICU.Subjects: Ninety-nine critically ill acute patients requiring percutaneous dilatational tracheotomy for mechanical ventilation.Interventions: Tracheal aspirate obtained 48 h before tracheotomy.Measurements and Main Results: Eighteen patients (18.1%) acquired pneumonia (median of 7 days after tracheotomy). Pseudomonas aeruginosa was the most frequently identified pathogen, found in eight of the episodes (four not documented by prior tracheal colonization), followed by other Gram-negative bacilli. The development of ventilator-associated pneumonia (VAP) was not anticipated by any clinical variable. A positive tracheal aspirate (TA) culture result obtained before tracheotomy was associated with a risk of acquiring pneumonia of 19.7%, whereas sterile TA cultures were associated with a risk of 14.3% (p > 0.20). VAP prolonged ICU stay or the ventilation period for a median of 19 days and 15 days, respectively. Overall mortality was 34.3%, but the presence of VAP did not increase the mortality rate.Conclusions: Percutaneous tracheotomy in patients receiving short-term mechanical ventilation predisposes to pneumonia. Pneumonia was associated with prolonged ventilation and ICU stay, but was not associated with increased mortality. Pseudomonas is a common pathogen after tracheotomy, and this observation should be considered in selecting an antibiotic regimen, because TA obtained prior to the tracheotomy often failed to identify this pathogen. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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