| Autor: |
Robinson SM, Batelaan SF, Syddall HE, Sayer AA, Dennison EM, Martin HJ, Barker DJ, Cooper C, Hertfordshire Cohort Study Group |
| Zdroj: |
American Journal of Clinical Nutrition; Jul2006, Vol. 84 Issue 1, p237-244, 8p |
| Abstrakt: |
BACKGROUND: Blood cholesterol responses to the manipulation of dietary fat vary widely between persons. Although epidemiologic evidence suggests that prenatal growth and nutrition influence adult cholesterol homeostasis, whether prenatal growth modifies the association between dietary fat intake and serum cholesterol concentration in adults is unknown. OBJECTIVE: The aim was to examine the relation between fat intake and serum cholesterol concentrations in men and women whose birth weights were known. DESIGN: We studied a cohort of men and women aged 59-71 y. Diet was assessed with a food-frequency questionnaire. Total, HDL-, and LDL-cholesterol concentrations and the ratio of HDL to LDL cholesterol were measured in fasting blood samples from 574 men and 562 women who did not have coronary heart disease. RESULTS: Total and saturated fat intakes were not associated with serum cholesterol concentrations in men or women. However, subdivision by birth weight showed associations in men but not in women. High intakes of total and saturated fat were associated with reduced HDL-cholesterol concentrations in men with birth weights
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| Databáze: |
Complementary Index |
| Externí odkaz: |
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