The Effect of Coenzyme Q[sub 10] Therapy in Parkinson Disease Could Be Symptomatic—Reply.

Autor: Shults, Clifford W., Haas, Richard, Oakes, David, Kieburtz, Karl, Plumb, Sandra, Shoulson, Ira, Kurlan, Roger, Beal, M. Flint, Juncos, Jorge, Watts, Ray, Nutt, John, Carter, Julie, Kompoliti, Katie, Perlmutter, Joel, Reich, Stephen, Stern, Matt, Molho, Eric, Harrison, Madeline, Lew, Mark
Předmět:
Zdroj: Archives of Neurology; Aug2003, Vol. 60 Issue 8, p1172, 2p
Abstrakt: The article focuses on comments by a group of doctors in response to the article "The effect of coenzyme Q10 (COQ10) therapy in Parkinson disease could be symptomatic," published in the August 2003 issue of the journal 'Arch Neurol.' A question regarding whether the effect on the total UPDRS score that was found in the study described in the article, could have been due to a symptomatic effect of CoQ10. They state that the neuroprotective effect been proposed in the previous article is not of great clinical importance because CoQ10 therapy apparently did not postpone levodopa treatment. A point is made by them stating that it may be appropriate to relate the effects of CoQ10 to the blood or tissue levels rather than to the dose as in the article. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index