| Autor: |
Bu'Lock FA, Sood M, De Giovanni JV, Green SH, Bu'Lock, F A, Sood, M, De Giovanni, J V, Green, S H |
| Zdroj: |
Archives of Disease in Childhood; Mar1999, Vol. 80 Issue 3, p267-270, 4p |
| Abstrakt: |
Objective: Examination of left ventricular function and conduction abnormalities in myotonic dystrophy.Design: Twelve patients (median age, 13.7 years) with myotonic dystrophy had detailed electrocardiography and echocardiography performed. Echocardiographic parameters were compared with body surface area (BSA) matched median normal values.Results: Fractional shortening was slightly reduced (by 28-29%) in three patients and three patients had mild mitral valve prolapse. Diastolic function was abnormal; isovolumic relaxation time (IVRT) and duration of early filling were prolonged compared with control values (median IVRT, 74 v 61 ms). Peak E velocity was increased (median, 0.82 v 0.78 m/s) but atrial phase filling was normal. Heart rate was reduced (median, 68 v 81 beats/min). Conduction abnormalities were common but showed no clear relations with diastolic abnormalities.Conclusions: Young patients with myotonic dystrophy have myocardial diastolic dysfunction as well as abnormal electrophysiology. The prognostic implications of such abnormalities require further study. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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