| Autor: |
Mittleman MA, Maclure M, Lewis MA, Hall GC, Moore N, Giuliano F, Porst H, Hedelin H, Martin-Morales A, Sobel RE, Reynolds R, Glasser DB |
| Zdroj: |
International Journal of Clinical Practice; Mar2008, Vol. 62 Issue 3, p367-373, 7p |
| Abstrakt: |
Aim: To assess the incidence of serious cardiovascular disease (CVD) events [i.e. myocardial infarction (MI) and stroke] and all-cause mortality in men with erectile dysfunction (ED) who received prescriptions for sildenafil. Methods: The International Men's Health Study (IMHS) was a prospective, observational cohort study of patients with ED and a new or existing prescription for sildenafil. Baseline and follow-up questionnaires provided information on demographics, CVD risk factors and ED. Postevent questionnaires were mailed to patients following possible nonfatal CVD events to collect information related to exposure to sildenafil/ED treatments before the event. Results: Thirty-five CVD events were reported in 30 patients in the analysis set ( n = 3813). The incidence of all-cause mortality, MI and stroke was 0.4, 0.6 and 0.1 per 100 patient-years of observation respectively. Among the six men who reported using sildenafil in the month before a nonfatal CVD event, two reported use in the 24 h before the event. Conclusion: The results of the IMHS support previous reports that ED and CVD are often comorbid and share risk factors. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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