| Autor: |
Schneidereit, Nathan P., Davis, Noelle, Mackinnon, Murray, Speers, Caroline H., Truong, Pauline T., Olivotto, Ivo A. |
| Předmět: |
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| Zdroj: |
Archives of Surgery; Aug2003, Vol. 138 Issue 8, p832, 6p |
| Abstrakt: |
Hypothesis: Axillary dissection (AD) does not affect recurrence or survival in T1a breast cancer. Design: Cohort study comparing patients who underwent AD and those who did not. Setting: Provincial cancer agency. Patients: Six hundred ninety-one women with pathologically diagnosed T1a tumors. Main Outcome Measures: Rates of axillary metastases stratified according to grade and lymphovascular and/or neural invasion, rates of relapse, and disease-specific survival. Results: Grade 1, 2, and 3 tumors without lymphovascular and/or neural invasion had axillary nodal involvement rates of 0.7%, 7%, and 7.8% of patients, respectively; with lymphovascular and/or neural invasion, axillary nodes were involved in 9.1%, 39.3%, and 44.4%, respectively. No statistically significant differences were found between the cohorts in relapse rates (P = .70) or survival (P = .84). Conclusion: Higher tumor grade and lymphovascular and/or neural invasion increased the rate of nodal metastases in T1a tumors, but AD did not improve relapse rates or breast cancer–specific survival. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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