| Autor: |
Bala M, Prasad J, Singh S, Tiwari S, Sawhney RC |
| Zdroj: |
Journal of Herbs, Spices & Medicinal Plants; Apr-Jun2009, Vol. 15 Issue 2, p203-215, 13p |
| Abstrakt: |
The radioprotective effects of Hippophae rhamnoides (common name, sea buckthorn) leaf extract, designated SBL-1, were investigated in Swiss Albino strain 'A' mice. Against 100% mortality in whole-body irradiated (60Co-gamma-rays, 10 Gy) controls, a single dose of the SBL-1 rendered >90% survivors when administered 30 min before irradiation and 90% to 80% survivors when administered 1 to 4 h before irradiation. SBL-1 activated proliferation of hemopoietic stem cells countered a radiation-induced decrease in total thiols and an increase in free radicals in plasma and liver; inhibited lipid peroxidation, and normalized the liver alkaline phosphatase activity. This study demonstrated high radioprotective potential of H. rhamnoides leaves. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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