Overlapping features of eclampsia and postpartum angiopathy.

Autor: Fletcher JJ, Kramer AH, Bleck TP, Solenski NJ, Fletcher, Jeffrey J, Kramer, Andreas H, Bleck, Thomas P, Solenski, Nina J
Zdroj: Neurocritical Care; Oct2009, Vol. 11 Issue 2, p199-209, 11p
Abstrakt: Introduction: Postpartum cerebral angiopathy (PPA) is considered one of a diverse group of rare conditions termed "reversible cerebral vasoconstriction syndromes". Existing literature suggest considerable overlap in the manifestations of eclampsia and PPA.Methods: Retrospective case series review of PPA and eclampsia from a single neurosciences intensive care unit patient log identified over a consecutive 18-month period. A MEDLINE search (using OVID) of the English literature from 1950 through October 2008 was also performed.Results: Four patients who meet the obstetrical criteria for eclampsia and four patients whose clinical and radiographic features were consistent with PPA were identified. Twenty-eight patients with PPA were identified from the literature and showed significant clinical and radiographic overlap without cohort.Conclusion: Given the overlapping clinical, laboratory, and radiographical features of eclampsia and PPA, it is probable they share a similar underlying pathophysiological mechanism and represent different clinical expressions of the same pregnancy-related disorder. The obstetrical definition of eclampsia may be to strict when applied in the neurosciences intensive care unit. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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