| Autor: |
Sheu TG, Fry AM, Garten RJ, Deyde VM, Shwe T, Bullion L, Peebles PJ, Li Y, Klimov AI, Gubareva LV, Sheu, Tiffany G, Fry, Alicia M, Garten, Rebecca J, Deyde, Varough M, Shwe, Thein, Bullion, Lesley, Peebles, Patrick J, Li, Yan, Klimov, Alexander I, Gubareva, Larisa V |
| Zdroj: |
Journal of Infectious Diseases; 2011, Vol. 203 Issue 1, p13-17, 5p |
| Abstrakt: |
Two distinct genetic clades of seasonal influenza A(H1N1) viruses have cocirculated in the recent seasons: clade 2B oseltamivir-resistant and adamantane-susceptible viruses, and clade 2C viruses that are resistant to adamantanes and susceptible to oseltamivir. We tested seasonal influenza A(H1N1) viruses collected in 2008-2010 from the United States and globally for resistance to antivirals approved by the Food and Drug Administration. We report 28 viruses with both adamantane and oseltamivir (dual) resistance from 5 countries belonging to 4 distinct genotypes. Because of limited options for antiviral treatment, emergence of dual-resistant influenza viruses poses a public health concern, and their circulation needs to be closely monitored. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
