Oseltamivir-resistant pandemic (H1N1) 2009 virus, South Korea.

Autor: Yi H, Lee JY, Hong EH, Kim MS, Kwon D, Choi JH, Choi WY, Kim KS, Lee JK, Oh HB, Kang C, Yi, Hwajung, Lee, Joo Yeon, Hong, Eun Hye, Kim, Mi Seon, Kwon, Donghyok, Choi, Jang Hoon, Choi, Woo Young, Kim, Ki Soon, Lee, Jong Koo
Zdroj: Emerging Infectious Diseases; Dec2010, Vol. 16 Issue 12, p1938-1942, 5p
Abstrakt: To identify oseltamivir resistance, we analyzed neuraminidase H275Y mutations in samples from 10 patients infected with pandemic (H1N1) 2009 virus in South Korea who had influenza that was refractory to antiviral treatment with this drug. A neuraminidase I117M mutation that might influence oseltamivir susceptibility was detected in sequential specimens from 1 patient. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index