Recovery from sedation with remifentanil and propofol, compared with morphine and midazolam, for reduction in anterior shoulder dislocation.

Autor: Dunn, Mark J.G., Mitchell, Robin, DeSouza, Cyrus I.B., Drummond, Gordon B., Waite, Alasdair
Zdroj: Emergency Medicine Journal (EMJ); Jan2011, Vol. 28 Issue 1, p6-10, 5p
Abstrakt: Objective To compare recovery from sedation using remifentanil and propofol with our standard regimen of morphine and midazolam for closed reduction in shoulder dislocation in an ED. Methods We randomised 40 patients tor closed shoulder reduction to receive either remitentanil and propofol (R&PI (20 patients) or morphine and midazolam IM&Mi 120 patients). A suitably trained ED doctor gave the sedation. R&P patients received oxygen from a tightfitting facemask and MapJeson Ccircuit to prevent hypocapnia and thus reduce the risk of apnoea. Shoulder reduction was performed by another doctor with an ED nurse also present. We noted recovery times, pain and sedation scores, operative conditions, additional medication and adverse events. Results All patients given remitentanil and propotol had recovered within 30 min in contrast to the morphine and midazolam group where 17 of 20 patients had recovered after 60 min, the remainder requiring a total ot 90 min. Median recovery times were 15 min 195% CI 15 to 20) tor the remifentanil and propofol group, and 45 min (95% CI 29 to 48) for the morphine and midazolam group. Reduction conditions and scores for pain/distress did not differ between the groups. Seven patients required additional sedation (tour R&P, three M&M) to enable shoulder reduction. Five patients (three R&P, two M&M) had received analgesia prior to the procedure trom the ambulance service (one R&P, one M&M) and ED (two R&PI. Two patients given morphine and midazolam required flumazenil to counter oversedation. Conclusions Remifentanil and propofol reduces patient recovery time and provides equivalent operating conditions compared with morphine and midazolam for the reduction of anterior glenohumeral dislocation. [ABSTRACT FROM AUTHOR]
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