Computed tomography for the detection of free-floating thrombi in the right heart in acute pulmonary embolism.

Autor: Mansencal N, Attias D, Caille V, Desperramons J, Guiader J, El Hajjam M, Lacombe P, Abi Nasr I, Jardin F, Vieillard-Baron A, Dubourg O, Mansencal, Nicolas, Attias, David, Caille, Vincent, Desperramons, Julien, Guiader, Julie, El Hajjam, Mostafa, Lacombe, Pascal, Abi Nasr, Imad, Jardin, François
Zdroj: European Radiology; Feb2011, Vol. 21 Issue 2, p240-245, 6p
Abstrakt: Objectives: The aim of this study was to assess the prevalence of free-floating thrombi in the right heart (FFT) and the accuracy of computed tomography (CT) for their detection in pulmonary embolism (PE).Methods: We studied 340 consecutive patients presenting with PE. All patients underwent CT and echocardiography.Results: The prevalence of FFT was 3.5% in the global population of PE and 22% in high-risk PE. Dyspnoea, cardiogenic shock, cardiac arrest and tachycardia were more frequently found in patients with FFT (p = 0.04, p < 0.0001, p = 0.0003 and p = 0.01, respectively). Sensitivity and specificity of CT for the detection of FFT were 100% (95% confidence interval: 74%-100%) and 97% (95%-99%), whereas positive and negative predictive values were 57% (34%-78%) and 100% (99%-100%). Among patients with FFT, right ventricular dilation was always detected by CT, whereas no right ventricular dilation was found among patients with a false diagnosis of FFT performed by CT (p < 0.0001).Conclusion: Prevalence of FFT is 3.5% and differs according to the clinical presentation. Detection of FFT by CT is feasible and should lead to echocardiography being promptly performed for the confirmation of FFT. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index