Desferrioxamine-related ocular toxicity: a case report.

Autor: Simon S, Athanasiov PA, Jain R, Raymond G, Gilhotra JS, Simon, Sumu, Athanasiov, Paul A, Jain, Rajeev, Raymond, Grant, Gilhotra, Jagjit S
Zdroj: Indian Journal of Ophthalmology; Jul/Aug2012, Vol. 60 Issue 4, p315-317, 3p
Abstrakt: A 29-year-old lady receiving repeated blood transfusions for β thalassemia since childhood, presented with rapidly deteriorating symptoms of night blindness and peripheral visual field loss. She was recently commenced on high-dose intravenous desferrioxamine for reducing the systemic iron overload. Clinical and investigative findings were consistent with desferrioxamine-related pigmentary retinopathy and optic neuropathy. Recovery was partial following cessation of desferrioxamine. This report highlights the ocular side-effects of desferrioxamine mesylate and the need to be vigilant in patients on high doses of desferrioxamine. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index