Clinical significance of incidental colonic 18F-FDG uptake on PET/CT images in patients with gastric adenocarcinoma.

Autor: Shim JH, O JH, Oh SI, Yoo HM, Jeon HM, Park CH, Kim SH, Song KY, Shim, Jung Ho, O, Joo Hyun, Oh, Seong Il, Yoo, Han Mo, Jeon, Hae Myung, Park, Cho Hyun, Kim, Sung Hoon, Song, Kyo Young
Zdroj: Journal of Gastrointestinal Surgery; Oct2012, Vol. 16 Issue 10, p1847-1853, 7p
Abstrakt: Background and Objectives: We assessed the ability of positron emission tomography-computed tomography (PET/CT) to detect synchronous colonic pathology and determined the significance of 18F-fluorodeoxyglucose (18F-FDG) activity in the colon of gastric cancer patients.Methods: A total of 239 gastric cancer patients who underwent PET/CT and colonoscopy preoperatively were included. FDG uptake patterns on PET/CT were classified as (1) group A, focal; (2) group B, diffuse; and (3) group C, no uptake. The PET/CT findings were compared with the results of concurrent colonoscopy.Results: In group A, a total of 123 polyps of >0 mm were observed. Of these, nine polyps were colonic adenocarcinomas and six were high-grade dysplasia. The incidence of colonic adenocarcinomas was significantly higher in group A than in the other two groups (p = 0.037). There was a significant correlation between SUVmax values and incidence of colonic polyps of >10 mm (r = 0.471, p = 0.04). The distribution pattern of SUVmax in polyps with adenoma (>10 mm) was less homogenous than in polyps (>10 mm) with adenocarcinoma.Conclusions: The focal colonic FDG uptake in PET/CT requires colonoscopic confirmation. The suspicion of colonic malignancy increased in the presence of polyps >10 mm that showed a positive correlation with the SUVmax. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index