Efficacy and Tolerability of Clarema 1% Cream and Hirudoid 40000U.APTT Gel in the Topical Treatment of Haematomas and/or Subcutaneous Haematic Extravasations.

Autor: Polieri, Tiziana, Orsoni, Enrico, Saponati, Giorgio, Castellacci, Enrico
Zdroj: ISRN Orthopedics; 2012, p1-5, 5p
Abstrakt: Ninety-six caucasian both-gender patients with haematomas and/or subcutaneous haematic extravasation of traumatic or surgical origin were randomized to receive local treatment (max 10 days) with heparan sulfate cream or glycosaminoglycan-polysulphate (GAGPS) gel. Signs (oedema, disability, and colour of the lesion) and symptoms (pain at rest and at movement) (scored 0-3), the sum of the scores (primary end point), and the size of the lesion were evaluated at the baseline visit and afterwards every 5 days. The rate of the patients completely healed at the end of the study was also recorded. The results of the study showed that heparan sulfate 1% cream was comparable or superior to GAGPS gel in relieving signs and symptoms. No AEs were recorded. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index