Effectiveness of Abdominal Acupuncture for Patients with Obesity-Type Polycystic Ovary Syndrome: A Randomized Controlled Trial.
Autor: | Zheng, Yan-Hua, Wang, Xin-Hua, Lai, Mao-Hua, Yao, Hong, Liu, Hua, Ma, Hong-Xia |
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Předmět: |
OBESITY treatment
POLYCYSTIC ovary syndrome treatment ABDOMINAL physiology METFORMIN ACUPUNCTURE ALTERNATIVE medicine ANTHROPOMETRY CHOLESTEROL CLINICAL trials HIGH density lipoproteins HOMEOSTASIS INSULIN INSULIN resistance LONGITUDINAL method LOW density lipoproteins LUTEINIZING hormone MENSTRUATION HEALTH outcome assessment RESEARCH funding STATISTICAL sampling STATISTICAL hypothesis testing T-test (Statistics) TESTOSTERONE TRIGLYCERIDES WOMEN'S health STATISTICAL significance BODY mass index RANDOMIZED controlled trials TREATMENT effectiveness PRE-tests & post-tests WAIST-hip ratio DATA analysis software DESCRIPTIVE statistics |
Zdroj: | Journal of Alternative & Complementary Medicine; Sep2013, Vol. 19 Issue 9, p740-745, 6p |
Abstrakt: | Objective: To assess the effectiveness of abdominal acupuncture at the endocrine and metabolic level in patients with obesity-type polycystic ovary syndrome (PCOS). Methods: Eighty-six women from the First Affiliated Hospital of Guangzhou Medical College with a diagnosis of PCOS (body-mass index [BMI] ≥25 kg/m2) were randomly assigned to receive 6 months of abdominal acupuncture (once a day) or oral metformin (250 mg three times daily in the first week, followed by 500 mg three times daily thereafter). BMI, waist-to-hip ratio (WHR), ovarian volume, menstrual frequency, homeostasis model assessment for insulin resistance (HOMA-IR), and Ferriman-Gallwey score were measured at the beginning of the study and after 6 months of treatment. Luteotrophic hormone (LH), testosterone, follicle-stimulating hormone (FSH), fasting blood glucose, 2-hour Postprandial blood glucose, fasting insulin, 2-hour postprandial blood insulin, total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were also assessed. Results: According to the results at baseline and 6 months, BMI, WHR, Ferriman-Gallwey score, ovarian volume, luteotrophic hormone, ratio of luteotrophic hormone to follicle-stimulating hormone, testosterone, LDL-C, triglycerides, total cholesterol, fasting blood glucose, 2-hour postprandial blood glucose, fasting insulin, 2-hour postprandial blood insulin, and HOMA-IR were reduced significantly in the two groups ( p<0.05). Menstrual frequency and HDL-C ( p<0.05) increased significantly in both groups; follicle-stimulating hormone also increased in both groups, but the change was not significant ( p>0.05). The acupuncture group showed considerable advantages over the metformin group in terms of reduced BMI and WHR and increases in menstrual frequency ( p<0.05). Conclusion: Abdominal acupuncture and metformin improved the endocrine and metabolic function of patients with obesity-type PCOS. Abdominal acupuncture may be more effective in improving menstrual frequency, BMI, and WHR, with few adverse effects. [ABSTRACT FROM AUTHOR] |
Databáze: | Complementary Index |
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