127 A DESCRIPTIVE STUDY OF PATTERNS OF DISEASE AND CLINICAL OUTCOMES IN OLDER ADULTS ADMITTED TO MEDICAL WARDS IN A CENTRAL HOSPITAL IN MALAWI.

Autor: Allain, T. J., Aston, S., Mapurisa, G., Banda, N. P. K., Sakala, S., Gonani, A., Heyderman, R. S., Peterson, I.
Zdroj: Age & Ageing; Jun2014, Vol. 43 Issue suppl_1, pi35-i35, 1p
Abstrakt: Introduction: The Queen Elizabeth Central Hospital (QECH) is the largest hospital in Malawi; approximately 8,000 patients are admitted yearly on the adult medical wards. Infectious disease admissions dominate, however there is an emerging epidemic of non-communicable diseases. QECH has an electronic medical record (EMR) which records information on demographics, HIV status, diagnosis and outcome (discharged alive/died).Method: Diagnosis, HIV status, length of stay and outcome was extracted from the EMR and analysed according to age for the first 4 months of 2013.Results: There were 2142 admissions, of which 17% were ≥55 years. The 10 commonest diagnoses and mortality by diagnosis differed across age categories (table). Age was associated with all-cause mortality (p = 0.0212), peaking at 30% in the 50-54 age group. Analysis of the commonest diagnoses showed that pneumonia mortality was higher in those <45 years (15.7%) compared to those >45 years (8.7%), (p = 0.0249) whereas sepsis mortality increased with older age (p = 0.0230). Median length of stay (in live discharges) was 7 and 6 days respectively, among patients <55 years and 55 years (p = 0.05). Younger patients were more likely to know their HIV status (68% vs 42.2%) and if known were more likely to be HIV reactive (74.9% vs 46.4%).<55 years (n = 1779)≥55 years (n = 363)Diagnoses (ranked by prevalence)% MortalityDiagnoses (ranked by prevalence)% MortalityTuberculosis31.6Stroke17.9Pneumonia14.2Tuberculosis29.4Sepsis16.0Pneumonia13.3Meningitis33.3Heart failure16.0Anaemia22.6Hypertension20.8Gastroenteritis17.6Gastroenteritis26.3Malaria15.1Sepsis35.3Cancer15.8Anaemia18.8Diabetes18.8Cancer29.4Heart Failure29.4Chronic lung disease7.7Conclusions: These data reveal important differences in disease pattern, HIV prevalence and outcome between young and older adults. Further research is needed to understand the factors underlying these differences. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index